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Ultrasonic Homogenizers (Sonicators)

Harness the power of rapid ultrasonic vibrations to break apart cells, nanoparticles, and even complex emulsions—fast. Our Ultrasonic Homogenizers (Sonicators) deliver efficient, precise sample preparation. When time and accuracy matter, count on omni ultrasonic homogenizers to deliver consistently superior results.

ultrasonic homogenizers (SONICATORS)

Our Homogenizers Are Trusted by the World’s Top Labs

BAKO
Washing University
Regeneron
Pfizer
NIH
Mount Sinai
Abbvie

Get A Free Sample Bead Kit

For precision-driven research, trust Omni Bead Kits to deliver the cleanest and most effective solutions available.

For personalized recommendations, our expert team is always ready to assist. Contact us to ensure you choose the perfect kit for your needs today and get a free sample kit!

What Makes Our Ultrasonic Homogenizers So Effective?

Omni Ultrasonic Homogenizers use high-frequency sound waves transmitted through a probe to create microscopic bubbles in your sample. These bubbles form and collapse at lightning speed, generating intense shear and shock waves—a process known as cavitation.

 

The outcome? Cells burst open, particles disperse, and even challenging materials become uniform suspensions.

 

Key Benefits:

  • High-Efficiency Cell Disruption: Ideal for breaking down cells and subcellular structures in suspensions.
  • Versatile Applications: From DNA shearing (helpful in genetic analysis) to nanoparticle dispersion, emulsification, and deagglomeration.
  • Rapid Processing: Achieve faster, more consistent homogenization than many alternative methods.
  • User-Friendly: Lower cost and simpler setup compared to other homogenization technologies.

 

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Ultrasonic Homogenizers that Accelerate Your Work

Whether you’re preparing DNA, RNA, or protein extracts, our ultrasonic homogenizers deliver the power and precision you need. They’re a staple in research labs, biotech firms, and industrial facilities around the globe—thanks to their speed, reliability, and minimal maintenance requirements.

OM50 sonicator
om100-sonicator
homogenizers-om500-sonicator-homogenization-and-cell-lysing

Explore all of our bead mill homogenizers

Get A Free Sample Bead Kit

For precision-driven research, trust Omni Bead Kits to deliver the cleanest and most effective solutions available.

For personalized recommendations, our expert team is always ready to assist. Contact us to ensure you choose the perfect kit for your needs today and get a free sample kit!

Consumables for Tissue Homogenizers

Whatever homogenizers you have on your bench, you'll need to keep them topped up with lysing kits and/or probe tips. 

Not Sure Which of Our Tissue Homogenizers is Right for You? Connect with Us Today!

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Trusted by the World’s Top Labs

BAKO
Washing University
Regeneron
Pfizer
NIH
Mount Sinai
Abbvie
OMNI-bead-ruptor-elite-5-star-review

5.0 RATING

“Powerful homogenization in a small footprint. A must-have for every laboratory.” 


Application Area: Trace residue analysis in crop and environmental samples.


"Our Bead Ruptor has been an enormous time saver. Previously sample homogenization of multiple samples could be a bottleneck. Especially if multiple chemists needed to use our traditional homogenizers, which are expensive and take up a lot of bench space. The Bead Ruptor makes quick work of multiple samples at once."

 

– Steven Perez
   ADPEN Laboratories, Inc.

OMNI-bead-ruptor-elite-5-star-review

5.0 RATING

"Saved a great deal of time"

 

Application Area: Lyme disease surveillance results from adult ticks.


“We have been using the grinder quite a bit and have saved a great deal of time by using the device as opposed to hand macerating/grinding the samples.” 

 

– Noor Tietze
   Department of Environmental Health
   Santa Clara County 

OMNI-bead-ruptor-elite-5-star-review

5.0 RATING

“It is easier to use, safer (no solvent splashes), and quieter (no hearing protection required)”


Application Area: Homogenize animal tissues in organic solvents.


"We purchased this product to replace a traditional shearing homogenizer. It is easier to use, safer (no solvent splashes), and quieter (no hearing protection required). It is programmable, ensuring consistent handling of all samples. It processes up to 24 samples simultaneously. It is very powerful. We process most of our samples for two to three cycles at 10 to 15 seconds per cycle."

 

– Bonne Thompson
   UT Southwestern Med Ctr

SCHEDULE YOUR DEMO BELOW

Witness the revolutionary ELITE in action and see firsthand how it can supercharge your lab.

Book your personalized demo today – because excellence waits for no one.

Witness the revolutionary ELITE in action and see firsthand how it can supercharge your lab.

Book your personalized demo today – because excellence waits for no one.

ABOUT OMNI

Meet the Team 
Behind the Tissue Homogenizers. 

Our commitment to you isn’t just to close the deal and doesn’t end at purchase.

 

Experience world-class support, custom applications, and tailored protocols before, during and after the sale.

 

With Omni, you’re never alone on your scientific journey.

 

Frequently Asked Questions About Tissue Homogenizers

Have Questions About Tissue Homogenizers? We're here to help

What is a Homogenizer?

A Homogenizer is a specialized laboratory device designed to blend, mix, and emulsify materials. It's crucial in many fields for sample preparation, helping to ensure that substances are uniformly processed. Omni Homogenizers are commonly found in research and industrial labs.
In essence, they play a key role in preparing samples for analytical procedures. From breaking down tissues in molecular biology to mixing pharmaceutical formulations, these devices are indispensable. For instance, they can generate cell lysates to extract nuclear proteins or even mix ingredients for drug formulations.

What is the Purpose of a Homogenizer?

The fundamental purpose of a homogenizer is to ensure uniform distribution of particles within a sample. This is essential across various applications, from disrupting cells for nucleic acid extraction to creating stable emulsions in food products and ensuring consistent drug formulations. Homogenization eliminates regions of variability within the sample, allowing for accurate and reproducible results.

Homogenizers significantly improve sample quality and processing efficiency by reducing sample preparation time and increasing throughput. For instance, the Omni Prep Homogenizer's ability to process up to six samples simultaneously not only saves time but also ensures consistent and high-quality results. This efficiency is crucial in busy settings where time and accuracy are highly valued.




How Does a Homogenizer Work?

Homogenizers function by applying mechanical forces to disrupt and evenly distribute the components within a sample. They use high-speed rotors or ultrasonic waves, depending on the model, to break down materials.

A typical Omni Homogenizer operates on the rotor-stator principle. The rotor moves at high speeds, creating strong shear forces as the sample passes between the rotor and the stationary stator. This action disrupts cells and particles, resulting in a uniform mixture.

There are other types, like ultrasonic homogenizers, which use sound waves to break down particles. These waves create cavitation bubbles in the sample, and their collapse generates shockwaves that disrupt the materials. This method is particularly effective for lysing cells and breaking down tough materials.

What Are Common Applications of Omni Homogenizers?

Omni homogenizers are essential tools in biological labs, particularly for cell lysis, which is the process of breaking down cell walls to extract DNA or RNA. This process is crucial for many downstream applications such as PCR, sequencing, and genotyping. Utilizing an Omni homogenizer ensures a uniform breakdown of cells which avoids the risk of uneven nucleic acid yield.

 

For protein studies, homogenizing samples to uniform consistency is key. Omni homogenizers provide consistent particle size reduction which is vital for protein analysis. Whether dealing with tissue samples, bacterial cultures, or plant materials, achieving a consistent and fine homogenate allows for better protein solubilization and subsequent purification.

In pharmaceutical labs, homogenizers play a pivotal role in drug formulation. One critical step is ensuring that active pharmaceutical ingredients (APIs) are uniformly distributed within the formulation paste. Proper homogenization ensures the efficacy and safety of the final pharmaceutical product. This uniform distribution impacts bioavailability and therapeutic effectiveness.

What Are Some Advantages of Using Omni Homogenizers?

Omni homogenizers drastically shorten the time it takes to process samples. For example, Omni homogenizers can homogenize most samples in under 60 seconds. 

Reducing sample processing time directly impacts overall research efficiency. Faster sample preparation means more samples can be processed in a day, which is crucial in both research and industrial settings. This efficiency not only benefits individual researchers but also scales up the productivity of entire laboratories.

Achieving a uniform particle size reduction is essential for the reproducibility of research. Omni homogenizers excel in this area. Many models can reduce particle sizes to 1 to 2 μm, ensuring consistency across samples. This is especially important in fields like molecular biology and pharmacology, where even minor variations can lead to significant differences in outcomes.

One of the standout features of Omni homogenizers is their versatility. They are compatible with a wide range of generator probes and chambers, making them suitable for diverse applications. This versatility extends to the scale of operations as well. 

This adaptability means that a single Omni homogenizer can be used for various types of research, from small-scale lab experiments to large-scale industrial applications. This makes them a cost-effective choice for institutions that require flexible and reliable sample preparation tools.

Omni homogenizers come with several innovative features designed to streamline lab operations and enhance sample integrity. For example, the patented Omni Tip, a disposable plastic generator probe, eliminates cross-contamination between samples, which is critical in protocols like nucleic acid extraction. 

These features not only save time but also reduce the risk of human error, which can compromise sample integrity. This makes Omni homogenizers particularly valuable for high-stakes research where precision is non-negotiable.

Omni homogenizers are designed to be scalable, catering to both small and large sample volumes. This is evident in models like the Omni Mixer and Macro Homogenizer, which can handle a range from 0.25 ml to 30 liters. This scalability is vital for labs that need to transition from small-scale experiments to larger production runs without investing in completely new equipment.