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BEAD RUPTOR CRYO COOLING UNIT

brcryo

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BEAD RUPTOR CRYO COOLING UNIT

SKU: 19-8005

COOLING SYSTEM TO PROTECT HEAT SENSITIVE SAMPLES DURING HOMOGENIZATION

 

The BR Cryo Cooling Unit is compatible with the Bead Ruptor Elite and is designed to prevent the increase of sample temperature during the homogenization process. The friction generated through the bead milling process generates heat that is imparted to the sample. In order to maintain a constant processing temperature during homogenization, the BR-Cryo passes chilled air (-100°C to -50°C) into the sample processing chamber and across the sample tubes to dissipate heat.

 

Samples can be maintained at a temperature ranging from 4°C to ambient thus protecting heat sensitive samples such as RNA and proteins. 

 

The BR Cryo can be used to maintain a constant temperature when extracting functional enzymes or volatile small molecules.

 

The BR Cryo Cooling Unit is not compatible with Tube Carriages > 7 mL or the 48 Position 2 mL Carriage

  • Dimensions: W: 9.0” (22.9 cm), D: 13.5” (34.3 cm), H: 11.5” (29.2 cm)
  • Weight: 16 lbs. (7.2 kg)
  • Cryo Chamber Volume:  1 L
  • Air Source Requirements: Compressed medical dry air (water < 5 ppm)
  • Air Source Pressure: 120 PSI
  • Cooling Source: Liquid Nitrogen or Dry Ice in Ethanol
  • Liquid Nitrogen Consumption: 1 L per 5 min of homogenization time
  • Dry Ice Consumption: 1 L of 0.5 L ethanol + 0.5 L dry ice per 90 minutes of homogenization time
  • Tube Compatibility: 0.5, 1.5, 2 x 24 and 7 mL Tube Carriages Only. Not compatible with tube sizes >7 mL or 48 Position 2 mL Carriage
  • Instrument Compatibility: BR Cryo is compatible with Bead Ruptor Elite (19-042E)
  • Warranty: One Year
  • Standards Approval: CE & UKCA Approved
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Bead Ruptor 24 Cryo Cooling Unit Overview

  • Compatible with the Bead Ruptor 24
  • Adjustable cooling rate
  • Compatible with liquid nitrogen or dry ice with ethanol
  • BR-Cryo maintain sample temperatures from 4°C to ambient
  • Prevent protein degradation
  • Ensure RNA stability
  • Prevent enzyme activation
sample_temp_processing_time

Intra-tube temperature monitoring during bead mill homogenization. 2 mL Omni reinforced tubes containing five 2.8 mm ceramic beads (Cat # 19-628) were filled with 1 mL H2O and processed at 7 m/s on the Bead Ruptor 24 for increasing time periods. Homogenization was performed with and without the use of the BR-Cryo cooling unit using liquid nitrogen as the cryo source. Intra-tube temperatures were monitored at each time point.

Trusted by the World’s Top Labs

BAKO
Washing University
Regeneron
Pfizer
NIH
Mount Sinai
Abbvie

Trusted by the World’s Top Labs

BAKO
Washing University
Regeneron
Pfizer
NIH
Mount Sinai
Abbvie
OMNI-bead-ruptor-elite-5-star-review

5.0 RATING

“Powerful homogenization in a small footprint. A must-have for every laboratory.” 


Application Area: Trace residue analysis in crop and environmental samples.


"Our Bead Ruptor has been an enormous time saver. Previously sample homogenization of multiple samples could be a bottleneck. Especially if multiple chemists needed to use our traditional homogenizers, which are expensive and take up a lot of bench space. The Bead Ruptor makes quick work of multiple samples at once."

 

– Steven Perez
   ADPEN Laboratories, Inc.

OMNI-bead-ruptor-elite-5-star-review

5.0 RATING

"Saved a great deal of time"

 

Application Area: Lyme disease surveillance results from adult ticks.


“We have been using the grinder quite a bit and have saved a great deal of time by using the device as opposed to hand macerating/grinding the samples.” 

 

– Noor Tietze
   Department of Environmental Health
   Santa Clara County 

OMNI-bead-ruptor-elite-5-star-review

5.0 RATING

“It is easier to use, safer (no solvent splashes), and quieter (no hearing protection required)”


Application Area: Homogenize animal tissues in organic solvents.


"We purchased this product to replace a traditional shearing homogenizer. It is easier to use, safer (no solvent splashes), and quieter (no hearing protection required). It is programmable, ensuring consistent handling of all samples. It processes up to 24 samples simultaneously. It is very powerful. We process most of our samples for two to three cycles at 10 to 15 seconds per cycle."

 

– Bonne Thompson
   UT Southwestern Med Ctr

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