Blast Through Your Biggest Bottlenecks
Maximize Multi-Sample Throughput with the Omni LH 96
The Omni LH 96 Automated Sample Prep Workstation is your tube-to-plate solution for overcoming bottlenecks in multi-sample homogenization.
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WHAT THEY'RE SAYING:
LH 96 pro user
“Implementation of the LH 96 resulted in ~40% increase in throughput.”
From Core Labs to Clinical Breakthroughs: Automate Your Sample Prep Workflow for Consistent, Reliable Results
Automate Precision, Productivity, and Performance
Whether you're scaling up for Phase 1 studies or managing core lab operations, the LH 96 bridges the gap between your current workflow and future goals by delivering repeatable, high-throughput sample preparation.
The Omni LH 96 Automated Homogenizer Workstation completely revolutionizes tissue homogenization by automating the weighing, lysis buffer addition, and homogenization and reformatting of tissue samples.
The LH 96 significantly reduces manual labor, increases throughput, and ensures consistency in your lab results. Ideal for high-throughput biomedical research, the LH 96 provides consistent, reproducible tissue sample preparation while freeing up valuable analyst time.
Ideal for Core Labs and High-Throughput Environments
The Omni LH 96 is essential for any core lab—whether you’re in academia, pharma, or biotech.
With its ability to handle small tissue samples and automate DMPK and PK/PD workflows, this workstation is a game-changer for labs that need to process hundreds or even thousands of samples with minimal errors.
The LH 96 automates your entire tissue processing workflow: from getting the sample into the tube, to diluting based on weight or constant volume, and ensuring there’s no cross-contamination.
If you’re not using disposable plastic tubes, the Omni LH 96 also supports automated cleaning, making it ideal for tackling the labor-intensive process of homogenization and sample preparation.
HEAD-TO-HEAD COMPARISON
Manual Sample Prep vs LH 96
Typical Time Savings in Preparing 384 Samples
The comparison was created using tissue as the sample type (liver, spleen, lung, kidney, heart) that is processed for 45 seconds on the Omni LH 96 using plastic disposable Omni Tips.
Manual preparation, in the context of this comparison, is defined as using a handheld motorized tissue homogenizer to individually homogenize 1 sample at a time for a 45-second cycle. All pipetting/reformatting steps were considered using a single-channel pipette.
| Sample Processing Step | Time it Takes to Manually Prep (in min) | Time It Takes Using LH 96 (in min) |
|---|---|---|
| Sample Weighing | 720 | 650 |
| Buffer Addition, Homogenization, Sample Reformatting | 576 | 335 |
| Average Time Spent Cleaning Stainless Steel (SS) Probes Used in Manual Method1 | 19202 | – |
| Total Time Preparing and Cleaning | 3216 | 985 |
Sample Processing Step
Time It Takes to Manually Prep (in min)
Time It Takes Using LH 96
(in min)
Sample Weighing
720
650
Buffer Addition, Homogenization, Sample Reformatting
576
335
Average Time Spent Cleaning Stainless Steel (SS) Probes Used in Manual Method1
19202
–
Total Time Preparing and Cleaning
3216
985
Sample Processing Step
Time to Manually Prep
(in min)
Time It Takes Using LH 96
(in min)
Sample Weighing
720
650
Buffer Addition, Homogenization, Sample Reformatting
576
335
Average Time Spent Cleaning Stainless Steel (SS) Probes Used in Manual Method1
19202
–
Total Time Preparing and Cleaning
3216
985
1920
MINUTES SAVED CLEANING STAINLESS STEEL PROBES
311
MINUTES SAVED PREPARING SAMPLES USING OMNI TIPS
45
ADDITIONAL SAMPLES PROCESSED PER WEEK WITH THE LH 96
1 Stainless steel probes are typically used when manually creating tissue lysates using a motorized tissue homogenizer. Time spent cleaning these probes in-between samples can range depending on cleaning method from as little as 5 minutes to wipe down and clean probe vs. 1 hour to autoclave the probe.
2 Typical cleaning range a 5–60 minutes. Calculation assumes 5 minutes per sample.
Sample Weighing
Time It Takes to Manually Prep
720 minutes
Time It Takes Using LH 96
650 minutes
Manual preparation, in the context of this comparison, is defined as using a handheld motorized tissue homogenizer to individually homogenize 1 sample at a time for a 45-second cycle. All pipetting/reformatting steps were considered using a single-channel pipette.
Note: stainless steel probes are typically used when manually creating tissue lysates using a motorized tissue homogenizer. Time spent cleaning these probes in-between samples can range depending on cleaning method from as little as 5 minutes to wipe down and clean probe vs. 1 hour to autoclave the probe.
Onboard Dilution Automate precise dilution of samples directly within the system to streamline workflows and ensure accuracy and consistency.
Sample Arm Avoid contamination or loss of samples, while streamlining precision sample handling by automating the transfer of tubes and vials between stations.
Reagent Addition Precisely dispense specified volumes to samples, optimizing consistency and efficiency in laboratory protocols.
Homogenization Customize homogenization with adjustable speeds, unique probe movements, and power, ensuring thorough and consistent sample processing and sample integrity.
Active Cooling System Circulate glycol coolant at a consistent 4°C with an external heat exchanger, efficiently cooling 2ml, 5ml, 14/15ml, and 50ml tubes.
Passive Cooling Rack Maintain 2ml, 5ml, 14/15ml, and 50ml tubes at or below 4°C for 30-45 minutes at room temperature, with an insulated drawer and temperature readout.
Integrated Scale Automate precise sample measurements with an analytical balance readability to 1 mg, ensuring data logging of sample weights for accurate and efficient tracking within the specific requirements of your application
Reformatting Simplify sample reformatting by automatically adjusting sample containers and configurations, enhancing workflow flexibility and efficiency.
Onboard Dilution Automate precise dilution of samples directly within the system to streamline workflows and ensure accuracy and consistency.
Sample Arm Avoid contamination or loss of samples, while streamlining precision sample handling by automating the transfer of tubes and vials between stations.
Reagent Addition Precisely dispense specified volumes to samples, optimizing consistency and efficiency in laboratory protocols.
Homogenization Customize homogenization with adjustable speeds, unique probe movements, and power, ensuring thorough and consistent sample processing and sample integrity.
Integrated Scale Automate precise sample measurements with an analytical balance readability to 1 mg, ensuring data logging of sample weights for accurate and efficient tracking within the specific requirements of your application
Reformatting Simplify sample reformatting by automatically adjusting sample containers and configurations, enhancing workflow flexibility and efficiency.
Active Cooling System Circulate glycol coolant at a consistent 4°C with an external heat exchanger, efficiently cooling 2ml, 5ml, 14/15ml, and 50ml tubes.
Passive Cooling Rack Maintain 2ml, 5ml, 14/15ml, and 50ml tubes at or below 4°C for 30-45 minutes at room temperature, with an insulated drawer and temperature readout.
WHAT THEY'RE SAYING:
– LH 96 pro user
“The direct workload for analysts was reduced even greater, as there was no longer a need for tissue sectioning or pulverization.”
“Results showed that the LH 96 was comparable or even more efficient than traditional bead milling in homogenizing various tissue types.”
“Implementation of the LH 96 resulted in ~40% increase in throughput.”
TUBE-TO-PLATE MULTI-SAMPLE AUTOMATION
Solve Your Biggest Bottleneck
You invest too much in your scientists for them to spend their days on labor-intensive, time-consuming, inefficient sample prep, and that’s where the Omni LH 96 comes in.
It automates everything—homogenization, weighing, pipetting, and liquid handling—so your skilled personnel can focus on high-value tasks. No more tedious weighing and pipetting or inconsistent processes that could introduce high amounts of error.
The LH 96 provides repeatable, highly reliable results, which are essential when dealing with hundreds—or thousands—of samples.
WHAT THEY'RE SAYING:
– LH 96 pro user
“The best thing about the LH 96 is it saves time, cutting our processing time in half.”
“The LH 96 does the entire
front end of our sample prep. We can just walk away while it works. It’s pretty amazing.”
“…it works perfect. I have run several tests and have seen that there is no carryover between samples.”
Why Invest in Multi-Sample Automation?
Configurable, Flexible, and Built for Your Needs
The Omni LH 96 is a configurable system with modular deck designs to suit your specific workflow.
Choose from three different setups:
WHAT THEY'RE SAYING:
– LH 96 pro user
“With the LH 96 we can process 200 samples in two days or less, instead of three.”
“It compresses the homogenization segment, giving you more time to prepare for everything else.”
“They are trustworthy, personable, and down to Earth. The staff at Omni wants to get the job done so you can get your job done. They have the knowledge and expertise to do what they do.”
Complete Homogenization Automation—Every Step of the Way
From tissue homogenization to liquid handling, the Omni LH 96 fully automates every step.
The LH 96 guarantees efficiency and consistency, no matter your sample type, making it a critical tool for DMPK and PK/PD environments. This level of automation is essential for core labs in universities and pharmaceutical companies that handle mid- to high-throughput workflows.
Key Features of the LH 96
Process Up to 96 Samples at Once
Homogenize, weigh, and prepare samples faster than ever, with minimal manual intervention.
Dramatically Reduce Cross-contamination
Eliminate manual handling with automated probe cleaning, reducing risk of cross-contamination.
Error-free Repeatability
Get precise, consistent results every time, even with complex workflows.
Complete Automation
Automates homogenization, liquid handling, pipetting, and weighing for error-free sample preparation.
Wide Compatibility
Processes tissue samples from 2 to 50 mL with variable homogenization speeds up to 28,000 rpm.
Deck Customization
Choose from modular deck configurations, allowing you to leverage standard, passive cooling, or active cooling setups based on your workflow needs.
Scalable ROI
Maximize value by reducing time spent on manual prep and increasing your throughput.
Sample Types and Applications
The Omni LH 96 is essential for core labs in universities and pharmaceutical companies conducting pharmacokinetics, toxicology, and biomarker research.
It is ideal for small tissue homogenization in DMPK and PK/PD workflows, where precision and consistency are critical.
Designed for Phase 1 studies, it efficiently handles large sample volumes with high accuracy and reproducibility.
Used in biomedical research, it provides precise quantification of protein biomarkers through LC-MS.
It accelerates proteomics and biomarker discovery efforts, helping identify key therapeutic targets.
The LH 96 supports gene therapy (GTx) research by preparing consistent samples for accurate LC-MS analysis.
It is optimized for lipid nanoparticle research, which is critical for developing mRNA-based vaccines and therapeutics.
The system also plays a crucial role in the development of protein degraders (PROTACs), enabling reliable sample homogenization for downstream assays.
LH 96 Full Specifications
Sample Processing Capacity
- Automated homogenization of up to 96 samples per run
- Capable of processing 250 µL to 40 mL per sample
- Compatible with tube sizes ranging from 2 to 50 mL
Liquid Handling & Transfer
- Automated handling of up to four separate liquids
- Pipetting and liquid transfer automation for accurate sample prep
- Automated vial transfer for streamlined workflows
Weighing
- Integrated automated weighing system for precise sample mass measurements
- Supports tare weighing to ensure accurate liquid-to-sample ratio calculations
Homogenization Features
- Variable homogenization speed: from 500 to 28,000 rpm for complete tissue breakdown
- Unique oscillating motion to ensure thorough and repeatable homogenization of samples
- Compatible with 7 mm and 12 mm Omni Tips™ Plastic Disposable Probes, 5, 7, and 10 mm Stainless Steel Generator Probes, and Omni Tip™ Hybrid Probes
Modular Deck Configurations
- Available with three deck configurations: standard, with passive cooling, and with active cooling to suit different sample stability needs
Temperature Control
- Sample cooling and heating options to maintain sample integrity during preparation
- Active cooling system option to regulate temperature-sensitive workflows
Ultrasonic Cleaning
- Built-in ultrasonic cleaning bath for automated cleaning of stainless steel probes between sample runs
- Features flow through, static and ultrasonic cleaning tanks and overflow control
Customizable Workflow Profiles
- Create custom sample processing profiles through the interactive LH 96 software interface
- Profiles can be saved, modified, and deployed quickly for hands-free sample preparation
Software & Automation
- Full automation of every step, including homogenization, weighing, liquid handling, pipetting, and vial transfer
- Easy-to-use graphical user interface (GUI) for seamless operation and customization
Applications and Sample Types
- Ideal for DMPK, PK/PD, proteomics, and small tissue homogenization
- Suited for labs processing large volumes of samples for LC-MS analysis, toxicology, pharmacokinetics, and core lab workflows
Sample Processing Capacity
- Automated homogenization of up to 96 samples per run
- Capable of processing 250 µL to 40 mL per sample
- Compatible with tube sizes ranging from 2 to 50 mL
Liquid Handling & Transfer
- Automated handling of up to four separate liquids
- Pipetting and liquid transfer automation for accurate sample prep
- Automated vial transfer for streamlined workflows
Weighing
- Integrated automated weighing system for precise sample mass measurements
- Supports tare weighing to ensure accurate liquid-to-sample ratio calculations
Homogenization Features
- Variable homogenization speed: from 500 to 28,000 rpm for complete tissue breakdown
- Unique oscillating motion to ensure thorough and repeatable homogenization of samples
- Compatible with 7 mm and 12 mm Omni Tips™ Plastic Disposable Probes, 5, 7, and 10 mm Stainless Steel Generator Probes, and Omni Tip™ Hybrid Probes
Modular Deck Configurations
- Available with three deck configurations: standard, with passive cooling, and with active cooling to suit different sample stability needs
Temperature Control
- Sample cooling and heating options to maintain sample integrity during preparation
- Active cooling system option to regulate temperature-sensitive workflows
Ultrasonic Cleaning
- Built-in ultrasonic cleaning bath for automated cleaning of stainless steel probes between sample runs
- Optional sonic cleaning bath for thorough and convenient probe sanitation, minimizing cross-contamination
Customizable Workflow Profiles
- Create custom sample processing profiles through the interactive LH 96 software interface
- Profiles can be saved, modified, and deployed quickly for hands-free sample preparation
Software & Automation
- Full automation of every step, including homogenization, weighing, liquid handling, pipetting, and vial transfer
- Easy-to-use graphical user interface (GUI) for seamless operation and customization
Applications and Sample Types
- Ideal for DMPK, PK/PD, proteomics, and small tissue homogenization
- Suited for labs processing large volumes of samples for LC-MS analysis, toxicology, pharmacokinetics, and core lab workflows
ABOUT OMNI
Commitment to Support
At Omni, we don’t just sell products and disappear.
We pride ourselves on providing unrivaled customer support—our relationship with you goes far beyond the purchase. Our team of dedicated scientists and engineers works closely with you to ensure that your LH 96 is fully customized for your unique workflows.
From setup to troubleshooting, we offer personalized assistance every step of the way, ensuring seamless integration and maximum performance.
Unlike others in the industry, Omni’s support is proactive and ongoing, with experts readily available to provide real-time solutions and tailored guidance. When you choose Omni, you’re not just buying a product—you’re gaining a partner who’s as invested in your lab’s success as you are.
Ready to Break Through Your Lab's Bottlenecks?
Explore the full range of configurations and automation options available with the Omni LH 96.
Contact us today to get a demo and learn more about how the LH 96 can transform your lab.